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| DEMETRA CHRISTOU | |||||||||||||||||||||||||
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Research Interests
Cardiovascular-autonomic function in aging, obesity, metabolic syndrome, Type II diabetes
Effect of diet on endothelial function Effect of diet-induced weight loss on cardiovascular-autonomic function Effect of physical activity/exercise training on cardiovascular-autonomic function Role of the renin angiotensin aldosterone system in age- and obesity-related endothelial dysfunction |
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Publications*
1. McNeal CJ, Wilson DP, Christou D, Bush RL, Shepherd LG, Santiago J. The use of surrogate vascular markers in youth at risk for premature cardiovascular disease. Journal of Pediatric Endocrinology and Metabolism, In Press. 2. Christou DD and Seals DR. Decreased Maximal Heart Rate with Aging is Related to Reduced ß-adrenergic Responsiveness, but is Largely Explained by a Reduction in Intrinsic Heart Rate. Journal of Applied Physiology, 105: 24-29, 2008. 3. Silver A, Beske S, Christou DD, Donato A, Moreau K, Eskurza I, Gates PE, Seals DR. Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47phox expression and evidence of endothelial oxidative stress. Circulation, 115: 627-637, 2007. 4. Christou DD, Gentile CL, DeSouza CA, Seals DR, Gates PE. Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men. Circulation, 111: 1904-1914, 2005. 5. Christou DD, Gentile CL, DeSouza CA, Seals DR, Gates PE. Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men. Circulation, 112: author reply, e253-e254, 2005. 6. Christou DD, Jones PP, Jordan J, Diedrich A, Robertson D, Seals DR. Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men. Circulation, 111:494-498, 2005. 7. Gates PE, Gentile C, Seals D, Christou D. Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. Journal of Clinical Endocrinology and Metabolism, 89(3):author reply, 1485-6, 2004. 8. Bell C, Day D, Jones PP, Christou DD, Petitt DS, Osterberg K, Melby CL, Seals DR. High energy flux mediates the tonically augmented ß-adrenergic support of resting metabolic rate in habitually exercising older adults. Journal of Clinical Endocrinology and Metabolism, 89:3573-3578, 2004. 9. Christou DD, Jones PP, Pimentel A, & Seals DR. Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging. American Journal of Physiology Heart and Circulatory Physiology, 287:H1530-H1537, 2004. 10. Gates PE, Gentile C, Seals D, Christou D. Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. Journal of Clinical Endocrinology and Metabolism, 88(10):4884-90, 2003. Show All
* Publication was joint-authored with students |
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College of Education and Human Development Grants and Contracts (Current)
Endothelial Dysfunction in Older Adult Humans with the Metabolic Syndrome. DHHS-PHS-NIH (Federal) 2008/07/01 - 2010/06/30 Total Funding: 125,486. Role of Mineralocorticoid Receptors in Endothelial Dysfunction in Older Adults with Metabolic Syndrome. American Heart Association (Private) 2008/07/01 - 2010/06/30 Total Funding: 140,000. |
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Awards
(2003-2005). Postdoctoral Fellowship. Awarded by the American Heart Association for $82,192 for the project proposal entitled: Gender, Age and Autonomic Nervous System "Support" of Blood Pressure (2000-2000). The Laura J. Huelster Memorial Award. Awarded to the Ph.D candidate that has shown a high degree of academic excellence in the Ph.D program and an outstanding dissertation proposal. Department of Kinesiology, University of Illinois at Urbana-Champaign |
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Courses Taught
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HLKN Faculty
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HLKN Staff
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