JOHN LAWLER
Office#: 213A Heldenfels Hall
Mail Stop: 4243
Office Phone: (979) 862-2038
E-mail:
Primary Emphasis Area: Kinesiology
Vita: View Document
Web Site: http://redox.tamu.edu
Short Bio
1997-present Associate Professor,Department of Health and Kinesiology, Texas A&M University
1991-1997 Assistant Professor, Department of Health and Kinesiology, Texas A&M University
Research Interests
Exercise Protection of the Heart Against Oxidative Stress and Cell Loss
Exercise Training and Antioxidant Capacity
Nitric Oxide, Free Radicals and Skeletal Muscle Function
Oxidative Stress and Cardiovascular Disease
Oxidative Stress and Muscle Wasting
Publications (journal articles, books, book chapters)*

1. Hord, J., Y. Lee, R. Botchlett, J.H. Kim, JM Lawler. Lifelong exercise and mild caloric restriction against disruption of the dystrophin-glycoprotein complex (DGC) in skeletal muscle. Exp. Gerontology. 2016 Oct; 83:148-57

2. Lawler JM, D. Rodriguez, and JM Hord. Mitochondria in the Middle: Exercise Preconditioning Protection of Striated Muscle. Journal of Physiology. 594: 5161-5183

3. Hord, JM, Lawler JM. ROS and nNOS in the Regulation of Disuse-Induced Skeletal Muscle Atrophy. The Plasticity of Skeletal Muscle - From Molecular Mechanism to Clinical Applications. 2016

4. Lee, Y., J. Hord, HB Kwak, JH Kim, and JM Lawler. Exercise Training Reduces Age-Dependent Elevation of Angiotensin II Receptor Pathway and TGF-beta in the FBN Rat Heart. Experimental Gerontology. 70:163-73. 2015.

5. Kim, J.H., H.-B. Kwak, and J.M. Lawler. Lifelong wheel running and mild caloric restriction attenuate nuclear Endo-G in rat plantaris muscle. Experimental Gerontology. 69: 122-128, 2015.

6. Kwak, H,-B., Y, Lee, and J.-H. Kim, H. Van Remmen, A.G. Richardson and JM Lawler. MnSOD overexpression reduces fibrosis and pro-apoptotic signaling in the aging mouse heart. J Gerontology: Biological Sciences. 2014 Jul 11. pii: glu090.

7. Lawler, J.M., M. Kunst, K. Joshi, J. Hord, Y. Lee, R. Botchlett, A. Ramirez, and D.A. Martinez. Regulation of nNOS[181][181] translocation from the sarcolemma and remodeling during short-term mechanical unloading is dependent on oxidative stress in the rat soleus muscle. American Journal of Physiology 306: R470[48]13R482, 2014

8. Botchlett, R, JM Lawler, and G Wu. Arginine and citrulline in sports nutrition and health. In Nutrition and Enhanced Sports Performance: Recommendations for Muscle Building D. Bagchi, S. Nair, and CK Sen (Eds) pp 439-446, 2013

9. Kim, JH, LA Thompson, HB Kwak, JM Lawler. Contribution of oxidative stress to pathology in diaphragm and limb muscles with dystrophin deficiency. Neuromuscular Disorders. 34: 1-13, 2013

10. Kim, J.-H. and J.M. Lawler. Amplification of pro-inflammatory phenotype, damage, and weakness by oxidative stress in the diaphragm of mdx mice. Free Radical Biology & Medicine. 52: 1597-1606, 2012

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* Publication was joint-authored with students
Diss Publication was from a dissertation
ROS Publication was from a record of study

College of Education and Human Development Grants and Contracts (Current)

Redox Regulation of nNOS Translocation and Muscle Atrophy During Mechanical Unloading. (PI)
NASA-Washington (Federal)
2012/08/24 - 2017/08/22
Total Funding: 400,000.
Courses Taught
Former Doctoral Students
Wook Song (Fall, 2003), Ph.D.
Hyo Bum Kwak (Spring, 2008), Ph.D.
Jong Hee Kim (Summer, 2009), Ph.D.
Jeffrey Mack Hord (Fall, 2016), Ph.D.
Professional Leadership/Service (International/National)

(2013). Young Investor Award.  Rachel Botchlett

(2005). Advisory Council.  American College of Sports Medicine Research

(2000). Fellow.  American College of Sports Medicine

Awards

(2003). Recognition award.  American Physiological Society- Wook Song is student

(2003). Scholarships for research in the biology of aging.  Wook Song - student

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